DuPont Nutrition & Biosciences Announces New SPEZYME® HN Alpha-Amylase Blend

SPEZYME® HN offers ethanol producers a new alpha-amylase blend, designed for high performance in harsh liquefaction conditions

WILMINGTON, Del., June 10, 2020 – DuPont Nutrition & Biosciences today announced the launch of SPEZYME® HN, the latest in the SPEZYME® line of alpha amylase enzymes and a new inclusion in business’s  suite of XCELIS® Ethanol Solutions.

The SPEZYME® line is known for offering numerous advantages for ethanol producers, including robust liquefaction and significant viscosity reduction across a variety of temperatures and pH levels. For the new SPEZYME® HN blend – which combines an alpha-amylase with a thermostable phytase – that means delivering industry-leading liquefaction for dry grind ethanol plants operating under harsh conditions.

“This is a significant development for the industry right now, particularly following the success of Clean in Place (CIP) solutions that lead to lower cations in the ethanol production process, which has traditionally caused challenges for alpha-amylases,” said Josh Naylor, marketing coordinator, DuPont Biorefineries. “SPEZYME® HN is a unique alpha-amylase blend in that it is designed to perform extremely well in harsh low cation or high temperature liquefaction conditions. This gives plants unprecedented flexibility in how they run their front-end operations.”

SPEZYME® HN generates high dextrose equivalents (DEs) and starch solubility when liquefaction cation concentrations are far below the industry average. In fact, it produces higher DEs and lower slurry viscosity than competitive alpha-amylases at liquefaction temperatures up to 195 degrees Fahrenheit.

To learn more about SPEZYME® HN and other XCELIS® Ethanol Solutions from DuPont, visit or

About DuPont Nutrition & Biosciences
DuPont Nutrition & Biosciences applies expert science to advance market-driven, healthy and sustainable solutions for the food, beverage, dietary supplement and pharmaceutical industries. We also use cutting-edge biotechnology across a range of markets to advance bio-based solutions to meet the needs of a growing population, while protecting our environment for future generations. We are innovative solvers who help our customers turn challenges into high-value business opportunities. For more information: or

About DuPont

DuPont (NYSE: DD) is a global innovation leader with technology-based materials, ingredients and solutions that help transform industries and everyday life. Our employees apply diverse science and expertise to help customers advance their best ideas and deliver essential innovations in key markets including electronics, transportation, construction, water, health and wellness, food, and worker safety. More information can be found at

For further information contact:
Missy Abbott



This page is currently undergoing development. Please connect with us at

/content/dupont/amer/us/en/nutrition-biosciences/contact-us.html /content/dupont/amer/us/en/nutrition-biosciences/references/corporate-contact-us.html /content/dupont/amer/us/en/nutrition-biosciences/references/subscribe.html