DuPont Nutrition & Health Introduces HOWARU® Shape

Breakthrough Probiotic Clinically Proven to Trim Your Waist

Vitafoods Europe - booth E22

Today, DuPont Nutrition & Health(DuPont) announced the launch of HOWARU® Shape, an innovative probiotic formula clinically proven to reduce waist circumference in overweight adults.

In a clinical study, HOWARU® Shape, which contains 10 billion CFU Bifidobacterium lactis B420™, reduced waist circumference by up to one inch. When taken in combination with 12g Litesse® Ultra™ prebiotic fiber, HOWARU® Shape also was shown to reduce body fat mass and trunk fat. The study was conducted with 225 healthy volunteers (healthy, BMI 28–34.9) who were randomized into four groups (1:1:1:1), using a computer-generated sequence, for 6 months of double-blind, parallel treatment.

Probiotic strain B420™ has been demonstrated in-vitro to increase epithelial integrity1, a key function of the digestive tract. Litesse® Ultra™ prebiotic fiber has been shown in clinical studies to reduce energy intake2, increase satiety3 and decrease after-meal feelings of hunger4. Separately, and in combination, the probiotic strain B420™ and Litesse® Ultra™ demonstrate health benefits.

Clinically demonstrated benefits of HOWARU® Shape in combination with Litesse® Ultra™ versus placebo.

  • 4.5 percent reduction in total body fat mass

  • 6.7 percent reduction in trunk fat

  • 1 inch (2.6cm) reduction in waist circumference 

“DuPont continues to be the leader in scientific innovation with the broadest range of clinically documented probiotics, and HOWARU® Shape is the latest breakthrough,” said Anders Gron Norager, Director, Global Probiotics at DuPont. “In 2016, the global weight loss supplement market was an almost $5 billion category and growing, and we know these consumers are not just interested in dieting, they want overall health and wellness, which includes looking good. HOWARU® Shape is geared toward those who want to lose weight but need help. We’re proud to offer these customers a proven way to manage their body shape naturally.”

HOWARU® Shape does not contain stimulants and is proven safe, effective and well-tolerated. It is a highly stable product, and ideal for capsules or sachets. For more information on HOWARU® Shape, please visit

1 Putaala et al. Res Microbiol 2008

2 Hull et al 2012; Astbury et al 2013

3 Hull et al 2012; Olli et al 2015

4 Hull et al 2012; Olli et al 2015


DuPont Nutrition & Health combines in-depth knowledge of food and nutrition with current research and expert science to deliver unmatched value to the food, beverage and dietary supplement industries.  We are innovative solvers, drawing on deep consumer insights and a broad product portfolio to help our customers turn challenges into high-value business opportunities. More information is available at

DuPont (NYSE: DD) has been bringing world-class science and engineering to the global marketplace in the form of innovative products, materials, and services since 1802.  The company believes that by collaborating with customers, governments, NGOs, and thought leaders we can help find solutions to such global challenges as providing enough healthy food for people everywhere, decreasing dependence on fossil fuels, and protecting life and the environment.  For additional information about DuPont and its commitment to inclusive innovation, please visit

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